Spectroflurometric estimation of droxidopa bulk and pharmaceutical dosage form
: Droxidopa,Hydrochloride,HCl, spectrofluorimetry, validation
: Simple, accurate and precise method was developed and validated for the selected drug like Droxidopa. The method is based on the spectrofluorimetric estimation of Droxidopa in drug and dosage form. Fluorescence intensity for droxidopa was measured at the excitation wavelength λex 295 nm and emission wavelength λem 318nm. The calibration plot was obtained in the concentration range of 15 to 30 µg/mL for droxidopa. The obtained correlation coefficients are in the range of 0.999. The % recovery value are found to be 98% for droxidopa. Limit of detection and limit of quantification are found to be 1.3 and 4.0 ug/ml for droxidopa. The method was validated as per ICH guidelines and the results of validation parameters such as linearity, precision, accuracy, Limit of detection and limit of quantification indicates the suitability of the method for the routine analysis in drugs and dosage form.
"Spectroflurometric estimation of droxidopa bulk and pharmaceutical dosage form ", TIJER - TIJER - INTERNATIONAL RESEARCH JOURNAL (www.TIJER.org), ISSN:2349-9249, Vol.11, Issue 2, page no.a787-a790, February-2024, Available :https://tijer.org/TIJER/papers/TIJER2402100.pdf
Volume 11
Issue 2,
February-2024
Pages : a787-a790
Paper Reg. ID: TIJER_151366
Published Paper Id: TIJER2402100
Downloads: 000277
Research Area: Pharmacy All
Country: Hyderabad., Telangana, India
ISSN: 2349-9249 | IMPACT FACTOR: 8.57 Calculated By Google Scholar | ESTD YEAR: 2014
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.57 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: TIJER (IJ Publication) Janvi Wave
