Spectrofluorimetric quantification of ritonavir in bulk and pharmaceutical dosage form
Ritonavir, spectrofluorimetric, validation
A simple and sensitive spectrofluorimetric method has been developed for Ritonavir. Ritonavir exhibited good fluorometric intensities in solvents Methanol and 0.02 M SLS. This method was developed for estimation of Ritonavir at emission wavelength 349 nm, in 0.02 M SLS with linearity range of 0.2-3.2 μg/mL and good correlation coefficient of R2 value 0.9992. The limit of detection and limit of quantification for this method were 0.033 μg/mL and 0.10 μg/mL respectively. The developed method was statistically validated as per ICH guidelines. The %RSD value was found to be less than 2 for accuracy and precision studies. The results obtained were in good agreement with the labeled amounts of the marketed formulations. which was evidenced with %RSD value 0.009, The proposed analytical method is employed for routine quality control analysis of Ritonavir in tablet dosage forms.
"Spectrofluorimetric quantification of ritonavir in bulk and pharmaceutical dosage form", TIJER - TIJER - INTERNATIONAL RESEARCH JOURNAL (www.TIJER.org), ISSN:2349-9249, Vol.11, Issue 2, page no.a778-a783, February-2024, Available :https://tijer.org/TIJER/papers/TIJER2402098.pdf
Volume 11
Issue 2,
February-2024
Pages : a778-a783
Paper Reg. ID: TIJER_151363
Published Paper Id: TIJER2402098
Downloads: 000291
Research Area: Pharmacy All
Country: Hyderabad, Telangana, India
ISSN: 2349-9249 | IMPACT FACTOR: 8.57 Calculated By Google Scholar | ESTD YEAR: 2014
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 8.57 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: TIJER (IJ Publication) Janvi Wave
