“Isolation and Identification of Aspergillus terreus and Production of Lovastatin”

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Monal Ingawale
Nilesh Hiwale
Mansi Mali
Dr.Mukesh Tiwary
Dr.Mohan Waman

Abstract

          Statins are the secondary metabolites which are produced by some fungal strains and are widely employed for reducing elevated levels of cholesterol in blood plasma Lovastatin is a potent drug was the first statin accepted by United States Food and Drug Administration (USFDA) in 1987 as a hypercholesterolemic drug .Lovastatin, a naturally occurring secondary metabolite is commonly found in foods such as red yeast rice, oyster mushroom, and Pu-erh, although in low concentration, and is primarily used for the cure of dyslipidemia and the prevention of heart-associated diseases as well. Lovastatin is also produced by some specific higher fungi such as Aspergillus terreus, Pleorotus ostreatus, and closely associated Pleorotus species. Production of lovaststin was done by using solid state fermentation by using wheat  bran and rice bran .Maximum yield was obtained when  wheat bran was used as a substrate.

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How to Cite
Ingawale, M., N. Hiwale, M. Mali, D. Tiwary, and D. Waman. “‘Isolation and Identification of Aspergillus Terreus and Production of Lovastatin’”. Technix International Journal for Engineering Research, vol. 9, no. 8, Aug. 2022, pp. 49-64, https://tijer.org/index.php/tijer/article/view/305.
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Research Articles

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